Product Name :
ALK (W1503) Peptide Applications :
Blocking Background :
LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occuring in many non-Hodgkin’s lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development. Alternative Name :
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; ALK Swiss-Prot :
Q9UM73 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ALK (W1503). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3243 ALK (W1503) pAb.
ALK (W1503) Peptide Applications :
Blocking Background :
LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occuring in many non-Hodgkin’s lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development. Alternative Name :
ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; ALK Swiss-Prot :
Q9UM73 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ALK (W1503). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3243 ALK (W1503) pAb.
Blocking peptide available as BS3243PP