ABCD1 (D575) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ABCD1 (D575) Peptide Applications :
Blocking Background :
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1–4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD4 localizes to peroxisomes. Alternative Name :
ATP-binding cassette sub-family D member 1; Adrenoleukodystrophy protein; ALDP; ABCD1; ALD Swiss-Prot :
P33897 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ABCD1 (D575). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3271 ABCD1 (D575) pAb.
ABCD1 (D575) Peptide Applications :
Blocking Background :
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1–4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD4 localizes to peroxisomes. Alternative Name :
ATP-binding cassette sub-family D member 1; Adrenoleukodystrophy protein; ALDP; ABCD1; ALD Swiss-Prot :
P33897 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ABCD1 (D575). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3271 ABCD1 (D575) pAb.
Blocking peptide available as BS3271PP