FBP3 (R241) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FBP3 (R241) Peptide Applications :
Blocking Background :
Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation. Alternative Name :
Far upstream element-binding protein 3; FUSE-binding protein 3; FUBP3; FBP3 Swiss-Prot :
Q96I24 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FBP3 (R241). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3297 FBP3 (R241) pAb.
FBP3 (R241) Peptide Applications :
Blocking Background :
Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxylterminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation. Alternative Name :
Far upstream element-binding protein 3; FUSE-binding protein 3; FUBP3; FBP3 Swiss-Prot :
Q96I24 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FBP3 (R241). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3297 FBP3 (R241) pAb.
Blocking peptide available as BS3297PP