Product Name :
NCoA-7 (I454) Peptide Applications :
Blocking Background :
Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. NCoA-7 (nuclear receptor coactivator 7), also known as ESNA1 or ERAP140, is a 942 amino acid nuclear protein that enhances nuclear receptor transcriptional activities and coactivates several nuclear receptors including PPAR©, ERα, TRβ1 and RARα. Highly expressed in brain and weakly expressed in pancreas, bladder, ovary, spinal cord, prostate, mammary gland, ovary, uterus and stomach, NCoA-7 is a member of the OXR1 family and contains one LysM repeat and a TLD domain. Six NCoA-7 isoforms are known to exist due to alternative splicing events, and the gene encoding NCoA-7 maps to human chromosome 6q22.31 and mouse chromosome 10 A4. Alternative Name :
Nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; Estrogen nuclear receptor coactivator 1; NCOA7; ERAP140; ESNA1; Nbla00052; Nbla10993 Swiss-Prot :
Q8NI08 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NCoA-7 (I454). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3356 NCoA-7 (I454) pAb.
NCoA-7 (I454) Peptide Applications :
Blocking Background :
Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. NCoA-7 (nuclear receptor coactivator 7), also known as ESNA1 or ERAP140, is a 942 amino acid nuclear protein that enhances nuclear receptor transcriptional activities and coactivates several nuclear receptors including PPAR©, ERα, TRβ1 and RARα. Highly expressed in brain and weakly expressed in pancreas, bladder, ovary, spinal cord, prostate, mammary gland, ovary, uterus and stomach, NCoA-7 is a member of the OXR1 family and contains one LysM repeat and a TLD domain. Six NCoA-7 isoforms are known to exist due to alternative splicing events, and the gene encoding NCoA-7 maps to human chromosome 6q22.31 and mouse chromosome 10 A4. Alternative Name :
Nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; Estrogen nuclear receptor coactivator 1; NCOA7; ERAP140; ESNA1; Nbla00052; Nbla10993 Swiss-Prot :
Q8NI08 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NCoA-7 (I454). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3356 NCoA-7 (I454) pAb.
Blocking peptide available as BS3356PP