Product Name :
Plakophilin 2 (P663) Peptide Applications :
Blocking Background :
Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function. Alternative Name :
CTNND2; GT24; Neural Plakophilin Related Armadillo Repeat Protein; NPRAP Swiss-Prot :
Q99959 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Plakophilin 2 (P663). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3368 Plakophilin 2 (P663) pAb.
Plakophilin 2 (P663) Peptide Applications :
Blocking Background :
Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function. Alternative Name :
CTNND2; GT24; Neural Plakophilin Related Armadillo Repeat Protein; NPRAP Swiss-Prot :
Q99959 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Plakophilin 2 (P663). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3368 Plakophilin 2 (P663) pAb.
Blocking peptide available as BS3368PP