PR48 (E394) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PR48 (E394) Peptide Applications :
Blocking Background :
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions. The protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. PR48 is a 48 kDa regulatory subunit of protein phosphatase 2A (PP2A). PP2A activity is required for the initiation of DNA replication in yeast, viral, and vertebrate systems. PR48 localizes to the nucleus and binds specifically to Cdc6, a highly conserved protein which is required for the formation of prereplicative complexes. PR48 is considered to be involved in the dephosphorylation of Cdc6 by PP2A, a process important to the control of DNA replication in mammalian cell. Alternative Name :
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; Protein phosphatase 2A 48 kDa regulatory subunit; PP2A; subunit B; PR48 isoform; PPP2R3B; PPP2R3L; NY-REN-8; PPP2R3LY Swiss-Prot :
Q9Y5P8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PR48 (E394). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3395 PR48 (E394) pAb.
PR48 (E394) Peptide Applications :
Blocking Background :
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions. The protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. PR48 is a 48 kDa regulatory subunit of protein phosphatase 2A (PP2A). PP2A activity is required for the initiation of DNA replication in yeast, viral, and vertebrate systems. PR48 localizes to the nucleus and binds specifically to Cdc6, a highly conserved protein which is required for the formation of prereplicative complexes. PR48 is considered to be involved in the dephosphorylation of Cdc6 by PP2A, a process important to the control of DNA replication in mammalian cell. Alternative Name :
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; Protein phosphatase 2A 48 kDa regulatory subunit; PP2A; subunit B; PR48 isoform; PPP2R3B; PPP2R3L; NY-REN-8; PPP2R3LY Swiss-Prot :
Q9Y5P8 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PR48 (E394). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3395 PR48 (E394) pAb.
Blocking peptide available as BS3395PP