Product Name :
T-type Ca++ CP α1H (P492) Peptide Applications :
Blocking Background :
Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs). Alternative Name :
CACNA1H, Voltage-dependent T-type calcium channel subunit alpha-1H, Low-voltage-activated calcium channel alpha1 3.2 subunit, CACNA1H Swiss-Prot :
O95180 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide T-type Ca++ CP α1H (P492). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3413 T-type Ca++ CP α1H (P492) pAb.
T-type Ca++ CP α1H (P492) Peptide Applications :
Blocking Background :
Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs). Alternative Name :
CACNA1H, Voltage-dependent T-type calcium channel subunit alpha-1H, Low-voltage-activated calcium channel alpha1 3.2 subunit, CACNA1H Swiss-Prot :
O95180 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide T-type Ca++ CP α1H (P492). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3413 T-type Ca++ CP α1H (P492) pAb.
Blocking peptide available as BS3413PP