EMR1 (T860) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
EMR1 (T860) Peptide Applications :
Blocking Background :
The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G protein-coupled receptors, which includes CD97, EMR1(EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE and ETL. These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system. The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. It is detected as 160 kDa protein that undergoes extensive N-linked glycosylation as well as some O-linked glycosylation. The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages. Alternative Name :
Cell surface glycoprotein EMR1; EMR1 hormone receptor; EMR1; TM7LN3 Swiss-Prot :
Q14246 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide EMR1 (T860). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3425 EMR1 (T860) pAb.
EMR1 (T860) Peptide Applications :
Blocking Background :
The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G protein-coupled receptors, which includes CD97, EMR1(EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE and ETL. These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system. The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. It is detected as 160 kDa protein that undergoes extensive N-linked glycosylation as well as some O-linked glycosylation. The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages. Alternative Name :
Cell surface glycoprotein EMR1; EMR1 hormone receptor; EMR1; TM7LN3 Swiss-Prot :
Q14246 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide EMR1 (T860). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3425 EMR1 (T860) pAb.
Blocking peptide available as BS3425PP