Product Name :
mGluR-2/3 (N867)Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate. Alternative Name :
Metabotropic glutamate receptor 3,mGluR3,GRM3,GPRC1C, MGLUR3 Swiss-Prot :
Q14416/Q14832 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-2/3 (N867) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3430 mGluR-2/3 (N867)pAb .
mGluR-2/3 (N867)Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate. Alternative Name :
Metabotropic glutamate receptor 3,mGluR3,GRM3,GPRC1C, MGLUR3 Swiss-Prot :
Q14416/Q14832 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-2/3 (N867) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3430 mGluR-2/3 (N867)pAb .
Blocking peptide available as BS3430PP