Product Name :
Connexin 26 (H94) Peptide Applications :
Blocking Background :
Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, approximately half the cases of autosomal recessive non-syndromic hearing loss and a significant proportion of sporadic hearing loss can be linked to mutation in the gene encoding connexin 26. Alternative Name :
Gap junction beta-2 protein; Connexin-26; Cx26; GJB2 Swiss-Prot :
P29033 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Connexin 26 (H94). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3443 Connexin 26 (H94) pAb.
Connexin 26 (H94) Peptide Applications :
Blocking Background :
Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another. Consequently, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, dependent on the particular connexin that is effected. For instance, approximately half the cases of autosomal recessive non-syndromic hearing loss and a significant proportion of sporadic hearing loss can be linked to mutation in the gene encoding connexin 26. Alternative Name :
Gap junction beta-2 protein; Connexin-26; Cx26; GJB2 Swiss-Prot :
P29033 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Connexin 26 (H94). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3443 Connexin 26 (H94) pAb.
Blocking peptide available as BS3443PP