PI3K p110α (R519) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PI3K p110α (R519) Peptide Applications :
Blocking Background :
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of 85 kDa (p85) and 110 kDa (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins. Alternative Name :
PIK3CA; MGC142161; MGC142163; PI3K; p110-alpha; Phosphatidylinositol-4; 5-bisphosphate 3-kinase catalytic subunit alpha isoform; Phosphatidylinositol-4; 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha Swiss-Prot :
P42336 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PI3K p110α (R519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3456 PI3K p110α (R519) pAb.
PI3K p110α (R519) Peptide Applications :
Blocking Background :
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of 85 kDa (p85) and 110 kDa (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins. Alternative Name :
PIK3CA; MGC142161; MGC142163; PI3K; p110-alpha; Phosphatidylinositol-4; 5-bisphosphate 3-kinase catalytic subunit alpha isoform; Phosphatidylinositol-4; 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha Swiss-Prot :
P42336 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PI3K p110α (R519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3456 PI3K p110α (R519) pAb.
Blocking peptide available as BS3456PP