Nephrin (H892) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Nephrin (H892) Peptide Applications :
Blocking Background :
Nephrin is a member of the immunoglobulin family of cell adhesion molecules that localizes to opposing sites of the secondary foot processes formed by podocytes, a specialized epithelial cell that ensures size- and charge-selective ultrafiltration. The human nephrin gene maps to chromosome 19q13.1 and encodes a 1,241 amino acid protein that contains a transmembrane domain, 8 Ig-like modules, and 1 fibronectin III-like module. Nephrin is expressed in embryonic and adult kidneys and localizes to glomerular podocytes and the glomerular slit diaphragm. Nephrin stimulates mitogen-activated protein kinases and is enhanced by podocin, which binds to the cytoplasmic tail of nephrin. Alternative Name :
NPHS1; CNF; NEPHRIN; NPHN Swiss-Prot :
O60500 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Nephrin (H892). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3462 Nephrin (H892) pAb.
Nephrin (H892) Peptide Applications :
Blocking Background :
Nephrin is a member of the immunoglobulin family of cell adhesion molecules that localizes to opposing sites of the secondary foot processes formed by podocytes, a specialized epithelial cell that ensures size- and charge-selective ultrafiltration. The human nephrin gene maps to chromosome 19q13.1 and encodes a 1,241 amino acid protein that contains a transmembrane domain, 8 Ig-like modules, and 1 fibronectin III-like module. Nephrin is expressed in embryonic and adult kidneys and localizes to glomerular podocytes and the glomerular slit diaphragm. Nephrin stimulates mitogen-activated protein kinases and is enhanced by podocin, which binds to the cytoplasmic tail of nephrin. Alternative Name :
NPHS1; CNF; NEPHRIN; NPHN Swiss-Prot :
O60500 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Nephrin (H892). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3462 Nephrin (H892) pAb.
Blocking peptide available as BS3462PP