FAST (R410) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
FAST (R410) Peptide Applications :
Blocking Background :
The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGβ and activin, indicating that these FAST proteins mediate TFGβ induced signal transduction. Alternative Name :
FOXH1; FAST-1; FAST-2; FAST1; FAST2; HFAST-1 Swiss-Prot :
Q14296 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FAST (R410). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3463 FAST (R410) pAb.
FAST (R410) Peptide Applications :
Blocking Background :
The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGβ and activin, indicating that these FAST proteins mediate TFGβ induced signal transduction. Alternative Name :
FOXH1; FAST-1; FAST-2; FAST1; FAST2; HFAST-1 Swiss-Prot :
Q14296 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide FAST (R410). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3463 FAST (R410) pAb.
Blocking peptide available as BS3463PP