Product Name :
S100A10 (V52) Peptide Applications :
Blocking Background :
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication. Alternative Name :
42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG; MGC111133 Swiss-Prot :
P60903 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide S100A10 (V52). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3478 S100A10 (V52) pAb.
S100A10 (V52) Peptide Applications :
Blocking Background :
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication. Alternative Name :
42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG; MGC111133 Swiss-Prot :
P60903 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide S100A10 (V52). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3478 S100A10 (V52) pAb.
Blocking peptide available as BS3478PP