Product Name :
TLR4 (S441) Peptide Applications :
Blocking Background :
Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria. Alternative Name :
Toll-like receptor 4; hToll; CD284; TLR-4 Swiss-Prot :
O00206 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TLR4 (S441). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3489 TLR4 (S441) pAb.
TLR4 (S441) Peptide Applications :
Blocking Background :
Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria. Alternative Name :
Toll-like receptor 4; hToll; CD284; TLR-4 Swiss-Prot :
O00206 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TLR4 (S441). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3489 TLR4 (S441) pAb.
Blocking peptide available as BS3489PP