Product Name :
Defensin α4 (D27) Peptide Applications :
Blocking Background :
Human neutrophil alpha-defensins (also designated HNPs) are small, cationic,cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice.The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel. Alternative Name :
Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4; DEFA4; DEF4; α-defensin 4 Swiss-Prot :
P12838 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Defensin α4 (D27). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3497 Defensin α4 (D27) pAb.
Defensin α4 (D27) Peptide Applications :
Blocking Background :
Human neutrophil alpha-defensins (also designated HNPs) are small, cationic,cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice.The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel. Alternative Name :
Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4; DEFA4; DEF4; α-defensin 4 Swiss-Prot :
P12838 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Defensin α4 (D27). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3497 Defensin α4 (D27) pAb.
Blocking peptide available as BS3497PP