Product Name :
Cytokeratin 14 (Y151) Peptide Applications :
Blocking Background :
Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The α-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and in addition they aid in the characterization of malignant tumors. In Bowen’s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. Mutations in the gene encoding human Cytokeratin 14 lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility. Alternative Name :
Keratin, type I cytoskeletal 14; Cytokeratin-14; Short name=CK-14; Keratin-14; Short name=K14; KRT14; CK-14; CK 14; CK14; Cytokeratin-14; Cytokeratin 14; Cytokeratin14; Swiss-Prot :
P02533 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cytokeratin 14 (Y151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3500 Cytokeratin 14 (Y151) pAb.
Cytokeratin 14 (Y151) Peptide Applications :
Blocking Background :
Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The α-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and in addition they aid in the characterization of malignant tumors. In Bowen’s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. Mutations in the gene encoding human Cytokeratin 14 lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility. Alternative Name :
Keratin, type I cytoskeletal 14; Cytokeratin-14; Short name=CK-14; Keratin-14; Short name=K14; KRT14; CK-14; CK 14; CK14; Cytokeratin-14; Cytokeratin 14; Cytokeratin14; Swiss-Prot :
P02533 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cytokeratin 14 (Y151). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3500 Cytokeratin 14 (Y151) pAb.
Blocking peptide available as BS3500PP