Product Name :
IL-4 (A59) Peptide Applications :
Blocking Background :
Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNFβ and IFN-γ, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2, and IgG3. Alternative Name :
Interleukin-4; Interleukin 4; Interleukin4; B-cell stimulatory factor 1; BSF-1; BSF1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra; IL4 Swiss-Prot :
P05112 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IL-4 (A59). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3501 IL-4 (A59) pAb.
IL-4 (A59) Peptide Applications :
Blocking Background :
Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNFβ and IFN-γ, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2, and IgG3. Alternative Name :
Interleukin-4; Interleukin 4; Interleukin4; B-cell stimulatory factor 1; BSF-1; BSF1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra; IL4 Swiss-Prot :
P05112 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IL-4 (A59). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3501 IL-4 (A59) pAb.
Blocking peptide available as BS3501PP