Product Name :
SOCS-1 (V98) Peptide Applications :
Blocking Background :
The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the “SOCS box.” The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOC-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family. Alternative Name :
Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; Short name=JAB; STAT-induced STAT inhibitor 1; Short name=SSI-1; Tec-interacting protein 3; TIP-3; SSI1; TIP3; SOCS1 Swiss-Prot :
O15524 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SOCS-1 (V98). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3509 SOCS-1 (V98) pAb.
SOCS-1 (V98) Peptide Applications :
Blocking Background :
The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the “SOCS box.” The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOC-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family. Alternative Name :
Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; Short name=JAB; STAT-induced STAT inhibitor 1; Short name=SSI-1; Tec-interacting protein 3; TIP-3; SSI1; TIP3; SOCS1 Swiss-Prot :
O15524 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SOCS-1 (V98). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3509 SOCS-1 (V98) pAb.
Blocking peptide available as BS3509PP