SDF-1 (M93) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SDF-1 (M93) Peptide Applications :
Blocking Background :
SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes, but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven-pass, transmembrane domain proteins which include IL-8RA, IL-8RB and fusin (also designated LESTR or CXCR-4). Fusin is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. Fusin has been identified as the major co-receptor for T-tropic HIV-1, and SDF-1 has been shown to inhibit HIV-1 infection. Six human SDF-1 isoforms exist due to alternative splicing of CXCL12, the gene encoding SDF-1. Alternative Name :
CXCL12a; SDF-1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; PBSF; hIRH; CXCL12; SDF1; SDF1A; SDF1B Swiss-Prot :
P48061 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SDF-1 (M93). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3512 SDF-1 (M93) pAb.
SDF-1 (M93) Peptide Applications :
Blocking Background :
SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes, but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven-pass, transmembrane domain proteins which include IL-8RA, IL-8RB and fusin (also designated LESTR or CXCR-4). Fusin is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. Fusin has been identified as the major co-receptor for T-tropic HIV-1, and SDF-1 has been shown to inhibit HIV-1 infection. Six human SDF-1 isoforms exist due to alternative splicing of CXCL12, the gene encoding SDF-1. Alternative Name :
CXCL12a; SDF-1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; PBSF; hIRH; CXCL12; SDF1; SDF1A; SDF1B Swiss-Prot :
P48061 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SDF-1 (M93). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3512 SDF-1 (M93) pAb.
Blocking peptide available as BS3512PP