Product Name :
Integrin αV (P804) Peptide Applications :
Blocking Background :
The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several αV subfamily members, including αVβ3, αVβ5, αVβ1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis. Alternative Name :
CD51; MSK8; VNRA; VTNR; ITGAV Swiss-Prot :
P06756 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Integrin αV (P804). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3513 Integrin αV (P804) pAb.

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Blocking peptide available as BS3513PP