Caspase 12 (P99) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Caspase 12 (P99) Peptide Applications :
Blocking Background :
Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, caspase-14, and caspase-5/caspase-12. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 (also designated TY or ICErelIII) can cleave its own precursor, an activity that requires the cysteine 245 residue. The mouse homolog of caspase-5 is designated caspase-12. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon and stomach, indicating that caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. Alternative Name :
Inactive caspase-12; CASP-12; UNQ9415/PRO34398; CASP12; Caspase12 Swiss-Prot :
Q6UXS9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Caspase 12 (P99). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3542 Caspase 12 (P99) pAb.
Caspase 12 (P99) Peptide Applications :
Blocking Background :
Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, caspase-14, and caspase-5/caspase-12. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 (also designated TY or ICErelIII) can cleave its own precursor, an activity that requires the cysteine 245 residue. The mouse homolog of caspase-5 is designated caspase-12. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon and stomach, indicating that caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. Alternative Name :
Inactive caspase-12; CASP-12; UNQ9415/PRO34398; CASP12; Caspase12 Swiss-Prot :
Q6UXS9 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Caspase 12 (P99). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3542 Caspase 12 (P99) pAb.
Blocking peptide available as BS3542PP