Na+ CP type IIα (K1032) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Na+ CP type IIα (K1032) Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The α subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type IIα subunits are more abundant along axons. The β1 subunit of sodium channel type I is expressed in brain, skeletal and cardiac muscle. In the brain, β1 and β2 are highly expressed in Purkinje cells, and β1 is also expressed in the pyramidal cells of the deep cerebellar nuclei. Impaired voltage-gated sodium channels lead to a number of diseases including myotonia. Alternative Name :
SCN2A; NAC2; SCN2A1; SCN2A2; HBSC II; Sodium channel protein type 2 subunit alpha Swiss-Prot :
Q99250 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IIα (K1032). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3562 Na+ CP type IIα (K1032) pAb.
Na+ CP type IIα (K1032) Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The α subunits of sodium channels type I and III are predominantly expressed in neuronal cell bodies and proximal processes, while type IIα subunits are more abundant along axons. The β1 subunit of sodium channel type I is expressed in brain, skeletal and cardiac muscle. In the brain, β1 and β2 are highly expressed in Purkinje cells, and β1 is also expressed in the pyramidal cells of the deep cerebellar nuclei. Impaired voltage-gated sodium channels lead to a number of diseases including myotonia. Alternative Name :
SCN2A; NAC2; SCN2A1; SCN2A2; HBSC II; Sodium channel protein type 2 subunit alpha Swiss-Prot :
Q99250 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IIα (K1032). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3562 Na+ CP type IIα (K1032) pAb.
Blocking peptide available as BS3562PP