Cortactin (Y460) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Cortactin (Y460) Peptide Applications :
Blocking Background :
Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks. Alternative Name :
Src substrate cortactin; Amplaxin; Oncogene EMS1; CTTN; EMS1 Swiss-Prot :
Q14247 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cortactin (Y460). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3642 Cortactin (Y460) pAb.
Cortactin (Y460) Peptide Applications :
Blocking Background :
Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks. Alternative Name :
Src substrate cortactin; Amplaxin; Oncogene EMS1; CTTN; EMS1 Swiss-Prot :
Q14247 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cortactin (Y460). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3642 Cortactin (Y460) pAb.
Blocking peptide available as BS3642PP