Product Name :
Cardiotrophin-1 (H31) Peptide Applications :
Blocking Background :
Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development. Alternative Name :
Cardiotrophin-1; CT-1; CTF1; Cardiotrophin1; CT1; Cardiotrophin 1; CT 1; Swiss-Prot :
Q16619 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cardiotrophin-1 (H31). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3672 Cardiotrophin-1 (H31) pAb.
Cardiotrophin-1 (H31) Peptide Applications :
Blocking Background :
Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development. Alternative Name :
Cardiotrophin-1; CT-1; CTF1; Cardiotrophin1; CT1; Cardiotrophin 1; CT 1; Swiss-Prot :
Q16619 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Cardiotrophin-1 (H31). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3672 Cardiotrophin-1 (H31) pAb.
Blocking peptide available as BS3672PP