Product Name :
Mfn2 (F403) Peptide Applications :
Blocking Background :
MFN2 is an essential transmembrane GTPase which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton, plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. It plays an important role in the regulation of vascular smooth muscle cell proliferation. Defects in MFN2 lead to Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Alternative Name :
Mitofusin-2; EC=3.6.5.-; Transmembrane GTPase MFN2; CPRP1; KIAA0214; MFN2; Swiss-Prot :
O95140 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Mfn2 (F403). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3682 Mfn2 (F403) pAb.
Mfn2 (F403) Peptide Applications :
Blocking Background :
MFN2 is an essential transmembrane GTPase which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton, plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. It plays an important role in the regulation of vascular smooth muscle cell proliferation. Defects in MFN2 lead to Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Alternative Name :
Mitofusin-2; EC=3.6.5.-; Transmembrane GTPase MFN2; CPRP1; KIAA0214; MFN2; Swiss-Prot :
O95140 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Mfn2 (F403). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3682 Mfn2 (F403) pAb.
Blocking peptide available as BS3682PP