Product Name :
Neuropilin-2 (M373) Peptide Applications :
Blocking Background :
Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium. Alternative Name :
Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2; VEGF165R2; NRP2 Swiss-Prot :
O60462 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Neuropilin-2 (M373). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3687 Neuropilin-2 (M373) pAb.
Neuropilin-2 (M373) Peptide Applications :
Blocking Background :
Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium. Alternative Name :
Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2; VEGF165R2; NRP2 Swiss-Prot :
O60462 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Neuropilin-2 (M373). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3687 Neuropilin-2 (M373) pAb.
Blocking peptide available as BS3687PP