Product Name :
NEFL (I344) Peptide Applications :
Blocking Background :
Neurofilament-L (for neurofilament light polypeptide, or NF-L), a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and actin filaments. Alternative Name :
Neurofilament light polypeptide; NF-L; 68 kDa neurofilament protein; Neurofilament triplet L protein; NF68; NFL Swiss-Prot :
P07196 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NEFL (I344). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3693 NEFL (I344) pAb.
NEFL (I344) Peptide Applications :
Blocking Background :
Neurofilament-L (for neurofilament light polypeptide, or NF-L), a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and actin filaments. Alternative Name :
Neurofilament light polypeptide; NF-L; 68 kDa neurofilament protein; Neurofilament triplet L protein; NF68; NFL Swiss-Prot :
P07196 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide NEFL (I344). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3693 NEFL (I344) pAb.
Blocking peptide available as BS3693PP