ATP7A (H640) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ATP7A (H640) Peptide Applications :
Blocking Background :
ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin. Mutations in the ATP7A gene result in Menkes disease, which is fatal in early childhood. Alternative Name :
Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein; ATP7A; MC1; MNK Swiss-Prot :
Q04656 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ATP7A (H640). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3695 ATP7A (H640) pAb.
ATP7A (H640) Peptide Applications :
Blocking Background :
ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin. Mutations in the ATP7A gene result in Menkes disease, which is fatal in early childhood. Alternative Name :
Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein; ATP7A; MC1; MNK Swiss-Prot :
Q04656 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ATP7A (H640). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3695 ATP7A (H640) pAb.
Blocking peptide available as BS3695PP