PAH (R400) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PAH (R400) Peptide Applications :
Blocking Background :
The PAH gene encodes the enzyme phenylalanine hydroxylase (PAH), which converts phenylalanine to tyrosine and is the rate-limiting enzyme in phenylalanine catabolism. Mammalian PAH is a soluble, homotetrameric protein which is abundantly expressed in human liver. Deficiency of PAH activity results in the autosomal recessive disorder phenylketonuria (PKU), which is characterized by mental retardation unless a low phenylalanine diet is introduced early in life. The PAH gene, which maps to human chromosome 12q23.2, contains all the genetic information necessary to code for functional PAH, demonstrating that a single gene is involved in the classic disease phenotype. Alternative Name :
Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase Swiss-Prot :
P00439 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PAH (R400). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3704 PAH (R400) pAb.
PAH (R400) Peptide Applications :
Blocking Background :
The PAH gene encodes the enzyme phenylalanine hydroxylase (PAH), which converts phenylalanine to tyrosine and is the rate-limiting enzyme in phenylalanine catabolism. Mammalian PAH is a soluble, homotetrameric protein which is abundantly expressed in human liver. Deficiency of PAH activity results in the autosomal recessive disorder phenylketonuria (PKU), which is characterized by mental retardation unless a low phenylalanine diet is introduced early in life. The PAH gene, which maps to human chromosome 12q23.2, contains all the genetic information necessary to code for functional PAH, demonstrating that a single gene is involved in the classic disease phenotype. Alternative Name :
Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase Swiss-Prot :
P00439 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PAH (R400). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3704 PAH (R400) pAb.
Blocking peptide available as BS3704PP