Trypsin-3 (M166) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Trypsin-3 (M166) Peptide Applications :
Blocking Background :
In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3 is expressed in the brain in addition to the pancreas. Alternative Name :
Trypsin-3; Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV; PRSS4; TRY3; TRY4; PRSS3 Swiss-Prot :
P35030 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Trypsin-3 (M166). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3707 Trypsin-3 (M166) pAb.
Trypsin-3 (M166) Peptide Applications :
Blocking Background :
In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3 is expressed in the brain in addition to the pancreas. Alternative Name :
Trypsin-3; Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV; PRSS4; TRY3; TRY4; PRSS3 Swiss-Prot :
P35030 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Trypsin-3 (M166). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3707 Trypsin-3 (M166) pAb.
Blocking peptide available as BS3707PP