Product Name :
ZIP-kinase (K261) Peptide Applications :
Blocking Background :
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues. Alternative Name :
ZIPK; ZIP kinase; ZIP; FLJ36473; EC 2.7.11.1; Dlk; Death associated protein kinase 3; Death associated kinase 3; Dapk3; Dapk 3; DAP like kinase; DAP kinase 3 Swiss-Prot :
O43293 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ZIP-kinase (K261). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3724 ZIP-kinase (K261) pAb.
ZIP-kinase (K261) Peptide Applications :
Blocking Background :
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues. Alternative Name :
ZIPK; ZIP kinase; ZIP; FLJ36473; EC 2.7.11.1; Dlk; Death associated protein kinase 3; Death associated kinase 3; Dapk3; Dapk 3; DAP like kinase; DAP kinase 3 Swiss-Prot :
O43293 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ZIP-kinase (K261). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3724 ZIP-kinase (K261) pAb.
Blocking peptide available as BS3724PP