Product Name :
MDFI (P134) Peptide Applications :
Blocking Background :
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation. Alternative Name :
MyoD family inhibitor; I MF; I mfa Swiss-Prot :
Q99750 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MDFI (P134). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3882 MDFI (P134) pAb.
MDFI (P134) Peptide Applications :
Blocking Background :
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation. Alternative Name :
MyoD family inhibitor; I MF; I mfa Swiss-Prot :
Q99750 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MDFI (P134). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3882 MDFI (P134) pAb.
Blocking peptide available as BS3882PP