Malic enzyme 1 (Y500) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Malic enzyme 1 (Y500) Peptide Applications :
Blocking Background :
ME1 (Malic enzyme 1), also known as NADP-ME, MES or HUMNDME, is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family. Expressed ubiquitously with highest expression in liver and white adipose tissue, ME1 functions as an NADP-dependent enzyme that catalyzes the conversion of S-malate and NADP to pyruvate, carbon dioxide and NADPH (a reducing agent that participates in fatty acid biosynthesis). Through its ability to catalyze the reversible oxidative decarboxylation of malate, ME1 links the citric acid and glycolytic cycles. ME1 exists as a homotetramer that uses divalent metal cations, such as magnesium or manganese, as cofactors. The expression of ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet, indicating that ME1 may play an important role as a housekeeping protein within the cell. Alternative Name :
malic enzyme 1; NADP(+)-dependent; cytosolic; HUMNDME; MES Swiss-Prot :
P48163 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Malic enzyme 1 (Y500). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3886 Malic enzyme 1 (Y500) pAb.
Malic enzyme 1 (Y500) Peptide Applications :
Blocking Background :
ME1 (Malic enzyme 1), also known as NADP-ME, MES or HUMNDME, is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family. Expressed ubiquitously with highest expression in liver and white adipose tissue, ME1 functions as an NADP-dependent enzyme that catalyzes the conversion of S-malate and NADP to pyruvate, carbon dioxide and NADPH (a reducing agent that participates in fatty acid biosynthesis). Through its ability to catalyze the reversible oxidative decarboxylation of malate, ME1 links the citric acid and glycolytic cycles. ME1 exists as a homotetramer that uses divalent metal cations, such as magnesium or manganese, as cofactors. The expression of ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet, indicating that ME1 may play an important role as a housekeeping protein within the cell. Alternative Name :
malic enzyme 1; NADP(+)-dependent; cytosolic; HUMNDME; MES Swiss-Prot :
P48163 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Malic enzyme 1 (Y500). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS3886 Malic enzyme 1 (Y500) pAb.
Blocking peptide available as BS3886PP