p-Crk2 (Y221) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-Crk2 (Y221) Peptide Applications :
Blocking Background :
Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor I (IGF-I) and might be involved in the IGF-I receptor signalling pathway. Alternative Name :
Adapter molecule crk; Proto-oncogene c-Crk; p38 CRK; CRK; CRKII Swiss-Prot :
P46108 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Crk2 (Y221). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4055 p-Crk2 (Y221) pAb.
p-Crk2 (Y221) Peptide Applications :
Blocking Background :
Crk I and Crk II are encoded by the same gene, which undergoes alternative splicing to yield these two proteins, but differ in their biological activities. Crk II has less transforming activity than Crk I, although both Crk I and Crk II bind to many tyrosine-phosphorylated proteins that bind to GRB2. In addition, Crk II becomes rapidly tyrosine-phosphorylated in response to stimulation with insulin-like growth factor I (IGF-I) and might be involved in the IGF-I receptor signalling pathway. Alternative Name :
Adapter molecule crk; Proto-oncogene c-Crk; p38 CRK; CRK; CRKII Swiss-Prot :
P46108 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Crk2 (Y221). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4055 p-Crk2 (Y221) pAb.
Blocking peptide available as BS4055PP