p-EGFR (T654) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-EGFR (T654) Peptide Applications :
Blocking Background :
EGFR (Epidermal growth factor receptor, ErbB-1) is a receptor tyrosine kinase (RTK) that is one of four members of the EGFR/ErbB family of receptor tyrosine kinases. EGFR plays a key role in the regulation of essential normal cellular processes and in the pathophysiology of hyperproliferative diseases such as cancer. Activation of the EGFR signaling pathway has been linked with increased cell proliferation, angiogenesis, metastasis and decreased apoptosis. Phosphorylation of residue Thr654 (removal of the signal peptide) during PKC activation prevents binding of calmodulin. Alternative Name :
Epidermal growth factor receptor; EC=2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; ERBB; ERBB1; HER1; EGFR Swiss-Prot :
P00533 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-EGFR (T654). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4062 p-EGFR (T654) pAb.
p-EGFR (T654) Peptide Applications :
Blocking Background :
EGFR (Epidermal growth factor receptor, ErbB-1) is a receptor tyrosine kinase (RTK) that is one of four members of the EGFR/ErbB family of receptor tyrosine kinases. EGFR plays a key role in the regulation of essential normal cellular processes and in the pathophysiology of hyperproliferative diseases such as cancer. Activation of the EGFR signaling pathway has been linked with increased cell proliferation, angiogenesis, metastasis and decreased apoptosis. Phosphorylation of residue Thr654 (removal of the signal peptide) during PKC activation prevents binding of calmodulin. Alternative Name :
Epidermal growth factor receptor; EC=2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; ERBB; ERBB1; HER1; EGFR Swiss-Prot :
P00533 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-EGFR (T654). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4062 p-EGFR (T654) pAb.
Blocking peptide available as BS4062PP