p-SHP-2 (Y580) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-SHP-2 (Y580) Peptide Applications :
Blocking Background :
Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog. Alternative Name :
PTP 1D , PTP 2C , PTP-1D , PTP-2C , PTP1D , PTP2C , PTPN 11 , PTPN11 , PTPN11 , SAP2 , SH PTP2 , SH PTP3 , SH-PTP2 , SH-PTP3 , SH2 domain containing protein tyrosine phosphatase 2 , SHIP2 , SHP 2 , SHP-2 , Shp2 , SHPTP 2 , SHPTP2 , SHPTP3 , Swiss-Prot :
Q06124 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-SHP-2 (Y580). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4171 p-SHP-2 (Y580) pAb.
p-SHP-2 (Y580) Peptide Applications :
Blocking Background :
Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog. Alternative Name :
PTP 1D , PTP 2C , PTP-1D , PTP-2C , PTP1D , PTP2C , PTPN 11 , PTPN11 , PTPN11 , SAP2 , SH PTP2 , SH PTP3 , SH-PTP2 , SH-PTP3 , SH2 domain containing protein tyrosine phosphatase 2 , SHIP2 , SHP 2 , SHP-2 , Shp2 , SHPTP 2 , SHPTP2 , SHPTP3 , Swiss-Prot :
Q06124 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-SHP-2 (Y580). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4171 p-SHP-2 (Y580) pAb.
Blocking peptide available as BS4171PP