p-Vav (Y174) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-Vav (Y174) Peptide Applications :
Blocking Background :
The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Alternative Name :
Flk - 1 / KDR / VEGFR2; VEGFR-2; EC 2.7.10.1; Kinase insert domain receptor; Protein-tyrosine kinase receptor Flk-1; CD309 antigen; VEGFR2; 16542; Kdr; 6130401C07; Flk-1; Flk1; Krd-1; Ly73; VEGFR-2; VEGFR2; 3791; KDR; 191306; P35 Swiss-Prot :
P15498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Vav (Y174). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4204 p-Vav (Y174) pAb.
p-Vav (Y174) Peptide Applications :
Blocking Background :
The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Alternative Name :
Flk - 1 / KDR / VEGFR2; VEGFR-2; EC 2.7.10.1; Kinase insert domain receptor; Protein-tyrosine kinase receptor Flk-1; CD309 antigen; VEGFR2; 16542; Kdr; 6130401C07; Flk-1; Flk1; Krd-1; Ly73; VEGFR-2; VEGFR2; 3791; KDR; 191306; P35 Swiss-Prot :
P15498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Vav (Y174). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4204 p-Vav (Y174) pAb.
Blocking peptide available as BS4204PP