p-Caspase-6 (S257) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-Caspase-6 (S257) Peptide Applications :
Blocking Background :
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. The cleavage of this protein causes cell membrane malfunction, membrane blebbing and eventual cell death. Alternative Name :
Caspase-6; Caspase6; Caspase 6; CASP-6; poptotic protease Mch-2; Caspase-6 subunit p11; CASP6; MCH2 Swiss-Prot :
P55212 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Caspase-6 (S257). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4219 p-Caspase-6 (S257) pAb.
p-Caspase-6 (S257) Peptide Applications :
Blocking Background :
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. The cleavage of this protein causes cell membrane malfunction, membrane blebbing and eventual cell death. Alternative Name :
Caspase-6; Caspase6; Caspase 6; CASP-6; poptotic protease Mch-2; Caspase-6 subunit p11; CASP6; MCH2 Swiss-Prot :
P55212 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Caspase-6 (S257). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4219 p-Caspase-6 (S257) pAb.
Blocking peptide available as BS4219PP