p-PKC α (T638) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-PKC α (T638) Peptide Applications :
Blocking Background :
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η and θ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca2+. Alternative Name :
Protein kinase C alpha type; PKC-A; PKC-alpha; PRKCA; PKCA; PRKACA Swiss-Prot :
P17252 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-PKC α (T638). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4346 p-PKC α (T638) pAb.
p-PKC α (T638) Peptide Applications :
Blocking Background :
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η and θ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca2+. Alternative Name :
Protein kinase C alpha type; PKC-A; PKC-alpha; PRKCA; PKCA; PRKACA Swiss-Prot :
P17252 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-PKC α (T638). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4346 p-PKC α (T638) pAb.
Blocking peptide available as BS4346PP