p-SNAI 1 (S246) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-SNAI 1 (S246) Peptide Applications :
Blocking Background :
The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. Alternative Name :
SNAI1; SLUGH2; SNA; SNAH; Protein snail homolog 1; Zinc finger protein SNAI1 Swiss-Prot :
O95863 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-SNAI 1 (S246). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4606 p-SNAI 1 (S246) pAb.
p-SNAI 1 (S246) Peptide Applications :
Blocking Background :
The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. Alternative Name :
SNAI1; SLUGH2; SNA; SNAH; Protein snail homolog 1; Zinc finger protein SNAI1 Swiss-Prot :
O95863 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-SNAI 1 (S246). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4606 p-SNAI 1 (S246) pAb.
Blocking peptide available as BS4606PP