p-CD32-B (Y292) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-CD32-B (Y292) Peptide Applications :
Blocking Background :
CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers.3 a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils. Alternative Name :
Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCGR2B; CD32; FCG2; IGFR2; CD32B; Swiss-Prot :
P31994 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-CD32-B (Y292). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4667 p-CD32-B (Y292) pAb.
p-CD32-B (Y292) Peptide Applications :
Blocking Background :
CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers.3 a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils. Alternative Name :
Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32; FCGR2B; CD32; FCG2; IGFR2; CD32B; Swiss-Prot :
P31994 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-CD32-B (Y292). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4667 p-CD32-B (Y292) pAb.
Blocking peptide available as BS4667PP