p-Rel B (S552) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-Rel B (S552) Peptide Applications :
Blocking Background :
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFκB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites. Alternative Name :
Transcription factor RelB; I-Rel; RELB Swiss-Prot :
Q01201 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Rel B (S552). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4770 p-Rel B (S552) pAb.
p-Rel B (S552) Peptide Applications :
Blocking Background :
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFκB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites. Alternative Name :
Transcription factor RelB; I-Rel; RELB Swiss-Prot :
Q01201 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Rel B (S552). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4770 p-Rel B (S552) pAb.
Blocking peptide available as BS4770PP