Product Name :
p-Shb (Y246) Peptide Applications :
Blocking Background :
The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell. Specifically, the SH2 domain targets SH2 domain-containing proteins to tyrosinephosphorylated sites, an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function. Shb (SH2 domain-containing adapter protein b), Shd (SH2 domain-containing adapter protein d), She (SH2 domain-containing adapter protein e) and Shf(SH2 domain-containing adapter protein f) are SH2 domain-containing proteins that play various roles throughout the cell. Alternative Name :
SH2 domain-containing adapter protein B; SHB Swiss-Prot :
Q15464 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Shb (Y246). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4821 p-Shb (Y246) pAb.

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Blocking peptide available as BS4821PP