p-Hrs (Y216) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
p-Hrs (Y216) Peptide Applications :
Blocking Background :
Hrs is involved in intracellular trafficking and signal transduction and is associated with early endosomes. Hrs contains a phosphatidylinositol 3-phosphate-binding domain that contributes to its endosomal targeting, where Hrs co-localizes with Clathrin via a Clathrin box motif at the carboxy-terminus of Hrs. Hrs is essential for ventral folding morphogenesis and shares structual similarity to the yeast protein Vps27p, which is involved in vacuolar protein sorting. The human Hrs gene, which maps to chromosome 17q25, enodes a 777 amino acid protein. In Schwann cells, Hrs co-localizes at endosomes with the tumor suppressor protein schwannomin, suggesting a role for schwannomin in Hrs-mediated cell signaling. Alternative Name :
HGS; HRS; Protein pp110; Hrs; Hepatocyte growth factor-regulated tyrosine kinase substrate Swiss-Prot :
O14964 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Hrs (Y216). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4824 p-Hrs (Y216) pAb.
p-Hrs (Y216) Peptide Applications :
Blocking Background :
Hrs is involved in intracellular trafficking and signal transduction and is associated with early endosomes. Hrs contains a phosphatidylinositol 3-phosphate-binding domain that contributes to its endosomal targeting, where Hrs co-localizes with Clathrin via a Clathrin box motif at the carboxy-terminus of Hrs. Hrs is essential for ventral folding morphogenesis and shares structual similarity to the yeast protein Vps27p, which is involved in vacuolar protein sorting. The human Hrs gene, which maps to chromosome 17q25, enodes a 777 amino acid protein. In Schwann cells, Hrs co-localizes at endosomes with the tumor suppressor protein schwannomin, suggesting a role for schwannomin in Hrs-mediated cell signaling. Alternative Name :
HGS; HRS; Protein pp110; Hrs; Hepatocyte growth factor-regulated tyrosine kinase substrate Swiss-Prot :
O14964 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide p-Hrs (Y216). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS4824 p-Hrs (Y216) pAb.
Blocking peptide available as BS4824PP