Tuberin/ Tsc2 (S1260) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Tuberin/ Tsc2 (S1260) Peptide Applications :
Blocking Background :
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1254 of human TSC2. TSC2 is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Mutations in TSC2 lead to tuberous sclerosis complex. Alternative Name :
Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4 Swiss-Prot :
P49815 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tuberin/ Tsc2 (S1260). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5545 Tuberin/ Tsc2 (S1260) pAb.
Tuberin/ Tsc2 (S1260) Peptide Applications :
Blocking Background :
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1254 of human TSC2. TSC2 is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Mutations in TSC2 lead to tuberous sclerosis complex. Alternative Name :
Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4 Swiss-Prot :
P49815 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Tuberin/ Tsc2 (S1260). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5545 Tuberin/ Tsc2 (S1260) pAb.
Blocking peptide available as BS5545PP