AOX1 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
AOX1 Peptide Applications :
Blocking Background :
AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal dominant neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2. Alternative Name :
Aldehyde oxidase; Aldehyde oxidase 1; Azaheterocycle hydroxylase; AOX1; AO; AOX-1 Swiss-Prot :
Q06278 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AOX1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5612 AOX1 pAb.
AOX1 Peptide Applications :
Blocking Background :
AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide. Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical. Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal dominant neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem. Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2. This evidence suggests that AOX1 is a candidate gene for ALS2. Alternative Name :
Aldehyde oxidase; Aldehyde oxidase 1; Azaheterocycle hydroxylase; AOX1; AO; AOX-1 Swiss-Prot :
Q06278 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide AOX1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5612 AOX1 pAb.
Blocking peptide available as BS5612PP