Product Name :
BNIP-2 Peptide Applications :
Blocking Background :
BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. Alternative Name :
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BNIP2; BNIP 2; NIP2 Swiss-Prot :
Q12982 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BNIP-2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5630 BNIP-2 pAb.
BNIP-2 Peptide Applications :
Blocking Background :
BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. Alternative Name :
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BNIP2; BNIP 2; NIP2 Swiss-Prot :
Q12982 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BNIP-2. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5630 BNIP-2 pAb.
Blocking peptide available as BS5630PP