Product Name :
BST1 Peptide Applications :
Blocking Background :
BST-1 (bone marow stromal antigen-1) has been identified as a surface molecule that is GPI-anchored to the cell membrane of stromal cells. Both ADP-ribosyl cyclase and cADPR hydrolase activites have been demonstrated by BST-1. cADPR activity is a potential regulator of insulin secretion in pancreatic beta cells. Most pancreatic islet cells express BST-1, indicating a link between BST-1 and insulin secretion. BST-1 expression has also been found in a wide range of tissues including umbilical vein endothelial cells, monocytes and granulocytes. BST-1 expression in thymus tissue and on B and T cell progenitors undergoing gene rearrangement implicates BST-1 as a useful marker for lymphoid progenitor cells that are initiating gene rearrangement of their antigen receptors. BST-1 has also been shown to facilitate B cell growth and may act as a receptor. Alternative Name :
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD157; BST-1 Swiss-Prot :
Q10588 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BST1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5633 BST1 pAb.
BST1 Peptide Applications :
Blocking Background :
BST-1 (bone marow stromal antigen-1) has been identified as a surface molecule that is GPI-anchored to the cell membrane of stromal cells. Both ADP-ribosyl cyclase and cADPR hydrolase activites have been demonstrated by BST-1. cADPR activity is a potential regulator of insulin secretion in pancreatic beta cells. Most pancreatic islet cells express BST-1, indicating a link between BST-1 and insulin secretion. BST-1 expression has also been found in a wide range of tissues including umbilical vein endothelial cells, monocytes and granulocytes. BST-1 expression in thymus tissue and on B and T cell progenitors undergoing gene rearrangement implicates BST-1 as a useful marker for lymphoid progenitor cells that are initiating gene rearrangement of their antigen receptors. BST-1 has also been shown to facilitate B cell growth and may act as a receptor. Alternative Name :
ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD157; BST-1 Swiss-Prot :
Q10588 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BST1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5633 BST1 pAb.
Blocking peptide available as BS5633PP