Caspase 14 p10 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Caspase 14 p10 Peptide Applications :
Blocking Background :
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p19 and p10 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes. Alternative Name :
Caspase14; Caspase-14; CASP-14; Caspase-14 subunit p10; CASP14 Swiss-Prot :
P31944 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Caspase 14 p10. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5643 Caspase 14 p10 pAb.
Caspase 14 p10 Peptide Applications :
Blocking Background :
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p19 and p10 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes. Alternative Name :
Caspase14; Caspase-14; CASP-14; Caspase-14 subunit p10; CASP14 Swiss-Prot :
P31944 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Caspase 14 p10. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5643 Caspase 14 p10 pAb.
Blocking peptide available as BS5643PP